abbomax//100ug/602-960型
市场价：
¥4900.00
美元价：
2450.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Connexin 43 (pS368)
Cnx43; gap junction 43kDa heart protein
Download Product PDF MSDS Download Product PDFProduct Preparation
A synthetic peptide corresponding to the C-terminal region with a phosphorylated Serine368 of human Connexin 43.
Background
Gap junction proteins allow the intercellular communication among adjacent cells by passing through small molecules less than 1kDa. It is very important in regulating embryonic development, excitable cell contraction, tissue homeostasis, and normal cell growth and differentiation. Gap junctions are composed of integral membrane proteins from the connexin gene family. Approximately 20 members have been cloned and characterized in humans. During intercellular channel formation, six connexin proteins oligomerize into a hemi-channel or connexon followed by connexon trafficking to the plasma membrane. The intact channel is formed when one hemi-channel docks with a second in an opposing cell. Once assembled, groups of these intercellular channels (termed gap junctional plaques) mediate the passage of amino acids, second messengers, and other metabolites between the connected cytoplasmic domains. The channels can be gated in response to various stimuli, including changes in voltage, pH, and connexin phosphorylation. Regulation of gap junctional communication could occur by controlling any one of the steps mentioned above. Phosphorylation of members of the connexin family of gap junction proteins has been correlated with gap junction assembly.
PURIFICATION The Rabbit IgG is purified by site-modified Epitope Affinity Purification. | SPECIFICITY This antibody 43 kDa of Connexin 43 at phosphorylated Serine 368. It reacts with human, rat and mouse. The other species are not tested. |
FORMULATION This affinity purified antibody is supplied in sterile Tris-buffered saline (pH7.2) containing antibody stabilizer. | STORAGE The antibodies are stable for 12 months from date of receipt when stored at –20oC. The antibodies can be stored at 2oC-8oC for one month without detectable loss of activity.Avoid repeated freezing-thawing cycles. |
Gene ID
2697
Applications/Suggested Working Dilutions
Western Blot 0.1-1 µg/ml | ELISA 0.01-0.1 µg/ml | Immunoprecipitation 2-5µg/ml | IHC 2-10µg/ml | Flow cytometry 5-10µg/ml |
品牌介绍
Abbomax成立于2005年，是一家专业研发、生产、销售分子生物学试剂和提供生物科技CRO服务的高科技公司。产品主要包括抗体（一抗、二抗、磷酸化抗体）、蛋白多肽、脂质体、ELISA试剂盒、CellMax™ FFPE Cell Pellet Slide、TissueMax™ FFPE Cell Pellet Slide 等。这些产品受到了学术界的*好评。部分产品的详细列表：abbomax授权代理货号产品规格价格（美元）CellMax™ FFPE Cell Pellet Slide - A549T2102035$ 49.00CellMax™ FFPE Cell Pellet Slide - BT474T2101055$ 49.00CellMax™ FFPE Cell Pellet Slide - CaSkiT2103025$ 49.00CellMax™ FFPE Cell Pellet Slide - CHL-1T2106055$ 49.00
