abbomax/p16INK4a (CT)/100ug/500-6314R
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¥0.00
美元价：
0.00
产品分类：
标签抗体
公司分类：
Tag_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
p16INK4a (CT)
Cyclin-dependent kinase inhibitor 2A; CDKN2A; P14;
Download Product PDFProduct Preparation
A synthetic peptide corresponding to the C-terminus of human p16INK4a protein.
Background
The INK4 (inhibitor of cyclin-dependent kinase 4) family consists of four tumor-suppressor proteins: p15(INK4B),p16(INK4A), p18(INK4C), and p19(INK4D). While their sequences and structures are highly homologous, they showappreciable differences in conformational flexibility, stability, and aggregation tendency. p16 (INK4a, CDKN2A,cyclin dependent kinase inhibitor 2A) is a tumor suppressor gene that inhibits cdk4 and cdk6 which phosphorylate the Rb protein. P16INK4a overexpression has been demonstrated in cervical cancers as a result of functional inactivation of pRbThus, this antibody can be an important marker for dysplastic squamous and glandular cells of the cervix.
PURIFICATION The Rabbit IgG is purified by Epitope Affinity Purification | SPECIFICITY This antibody recognizes ~16-18 kDa of human p16INK4a protein. The other species are not tested |
FORMULATION This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer. | STORAGE The antibodies are stable for 12 months from date of receipt when stored at –20oC. The antibodies can be stored at 2oC-8oC for one month without detectable loss of activity.Avoid repeated freezing-thawing cycles. |
Gene ID
1029
Applications/Suggested Working Dilutions
Western Blot 0.1-1 µg/ml | ELISA 0.01-0.1 µg/ml | Immunoprecipitation 2-5µg/ml | IHC 2-10µg/ml | Flow cytometry 5-10µg/ml |
品牌介绍
Abbomax成立于2005年，是一家专业研发、生产、销售分子生物学试剂和提供生物科技CRO服务的高科技公司。产品主要包括抗体（一抗、二抗、磷酸化抗体）、蛋白多肽、脂质体、ELISA试剂盒、CellMax™ FFPE Cell Pellet Slide、TissueMax™ FFPE Cell Pellet Slide 等。这些产品受到了学术界的*好评。部分产品的详细列表：abbomax授权代理货号产品规格价格（美元）CellMax™ FFPE Cell Pellet Slide - A549T2102035$ 49.00CellMax™ FFPE Cell Pellet Slide - BT474T2101055$ 49.00CellMax™ FFPE Cell Pellet Slide - CaSkiT2103025$ 49.00CellMax™ FFPE Cell Pellet Slide - CHL-1T2106055$ 49.00
