abbomax/NFkB p65/100ug/500-2754
市场价：
¥0.00
美元价：
0.00
产品分类：
抗体套装
公司分类：
Antibody_set
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
NFkB p65
nuclear factor kappa B subunit p65; NFkB
Download Product PDFProduct Preparation
A synthetic peptide derived from internal domain of human NF?B p65.
Background
NF-?B (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls the transcription of DNA. NF-?B is important in regulating cellular responses because it belongs to the category of "rapid-acting" primary transcription factors. NF kappa B is a heterodimer consisting of a 50kDa DNA binding subunit and a 65kDa transactivating subunit. In unstimulated cells, the NF-?B dimers are sequestered in the cytoplasm by a family of inhibitors, called I?Bs (Inhibitor of ?B). Activation of the NF-?B is initiated by the signal-induced degradation of I?B proteins. Subsequent to cell stimulation, I?B undergoes phosphorylation, ubiquitination and degradation by a proteosome-dependent pathway, allowing nuclear translocation of the active dimeric NF?B transcription factor. NF-?B complex enters the nucleus where it can "turn on" the expression of specific genes that have DNA-binding sites for NF-?B nearby. The activation of these genes by NF-?B then leads to the given physiological response, for example, an inflammatory or immune response, a cell survival response, or cellular proliferation.
PURIFICATION The Rabbit IgG is purified by Epitope Affinity Purification | SPECIFICITY This antibody reacts with human, rat and rabbit.The other species are not tested. |
FORMULATION This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer. | STORAGE The antibodies are stable for 12 months from date of receipt when stored at –20oC. The antibodies can be stored at 2oC-8oC for one month without detectable loss of activity.Avoid repeated freezing-thawing cycles. |
Gene ID
5970
Applications/Suggested Working Dilutions
Western Blot 0.1-1 µg/ml | ELISA 0.01-0.1 µg/ml | Immunoprecipitation 2-5µg/ml | IHC 2-10µg/ml | Flow cytometry 5-10µg/ml |
品牌介绍
Abbomax成立于2005年，是一家专业研发、生产、销售分子生物学试剂和提供生物科技CRO服务的高科技公司。产品主要包括抗体（一抗、二抗、磷酸化抗体）、蛋白多肽、脂质体、ELISA试剂盒、CellMax™ FFPE Cell Pellet Slide、TissueMax™ FFPE Cell Pellet Slide 等。这些产品受到了学术界的*好评。部分产品的详细列表：abbomax授权代理货号产品规格价格（美元）CellMax™ FFPE Cell Pellet Slide - A549T2102035$ 49.00CellMax™ FFPE Cell Pellet Slide - BT474T2101055$ 49.00CellMax™ FFPE Cell Pellet Slide - CaSkiT2103025$ 49.00CellMax™ FFPE Cell Pellet Slide - CHL-1T2106055$ 49.00
