abbomax/I-Kappa-B Kinase b (IKKb)/100ug/500-7714
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美元价：
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产品分类：
内参抗体
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
I-Kappa-B Kinase b (IKKb)
I-Kappa-B Kinase b ; Inhibitor of kappa light poly
Download Product PDFProduct Preparation
The full length of human IKKß recombinant protein.
Background
IKK beta (I-Kappa-B kinase-beta) is a member of the IKK complex which is composed of IKK alpha, IKK beta, IKK gamma and IKAP.IKK is a serine protein kinase which can activate NF-kB. Phosphorylation of I-Kappa-B on a serine residue by the IKK complex frees NF-kB from I-Kappa-B and marks it for degradation via ubiquination. IKK beta has been shown to activate NF-kB and phosphorylate IKB alpha and beta. Phosphorylation of 2 sites at the activation loop of IKK beta is essential for activation of IKK by TNF and IL1. Once activated, IKK beta autophosphorylates which in turn decreases IKK activity and prevents prolonged activation of the inflammatory response. Additionally, IKK beta activity can also be regulated by MEKK1.
PURIFICATION The Rabbit IgG is purified by Epitope Affinity Purification | SPECIFICITY This antibody reacts with human, mouse and rat.The other species are not tested. |
FORMULATION This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer. | STORAGE The antibodies are stable for 12 months from date of receipt when stored at –20oC. The antibodies can be stored at 2oC-8oC for one month without detectable loss of activity.Avoid repeated freezing-thawing cycles. |
Gene ID
3551
Applications/Suggested Working Dilutions
Western Blot 0.1-1 µg/ml | ELISA 0.01-0.1 µg/ml | Immunoprecipitation 2-5µg/ml | IHC 2-10µg/ml | Flow cytometry 5-10µg/ml |
品牌介绍
Abbomax成立于2005年，是一家专业研发、生产、销售分子生物学试剂和提供生物科技CRO服务的高科技公司。产品主要包括抗体（一抗、二抗、磷酸化抗体）、蛋白多肽、脂质体、ELISA试剂盒、CellMax™ FFPE Cell Pellet Slide、TissueMax™ FFPE Cell Pellet Slide 等。这些产品受到了学术界的*好评。部分产品的详细列表：abbomax授权代理货号产品规格价格（美元）CellMax™ FFPE Cell Pellet Slide - A549T2102035$ 49.00CellMax™ FFPE Cell Pellet Slide - BT474T2101055$ 49.00CellMax™ FFPE Cell Pellet Slide - CaSkiT2103025$ 49.00CellMax™ FFPE Cell Pellet Slide - CHL-1T2106055$ 49.00
