abbomax/FOXA3/100ug/602-700
市场价：
¥0.00
美元价：
0.00
产品分类：
多克隆抗体
公司分类：
Polyclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
FOXA3
Forkhead box A3
Download Product PDFProduct Preparation
A synthetic peptide corresponding to the C-terminus of human FOXA3 protein. This sequence is identical to rat, mouse and human origins.
Background
The forkhead box gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. FOXA1 plays an important role in breast cancer.The FOXA subfamily is composed of the transcription factors FOXA1, A2, A3. They were discovered as the regulators of hepatic genes. Foxa1 has been shown to be required for glucagon secretion in the pancreas, whereas Foxa2 is critical for the regulation of insulin secretion in pancreatic beta-cells. Foxa3 is important in the maintenance of glucose homeostasis, it is the dominating transcriptional regulator of GLUT2 expression in hepatocytes in vivo. In the normal activation of HNF-4alpha, HNF-1alpha, and PGC-1 induced by fasting is attenuated in mice lacking Foxa3.
PURIFICATION The Rabbit IgG is purified by Epitope Affinity Purification | SPECIFICITY This antibody recognizes ~37 kDa of FOXA3 protein. It also reacts with human, mouse and rat. The other species are not tested. |
FORMULATION This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer. | STORAGE The antibodies are stable for 12 months from date of receipt when stored at –20oC. The antibodies can be stored at 2oC-8oC for one month without detectable loss of activity.Avoid repeated freezing-thawing cycles. |
Gene ID
3171
Applications/Suggested Working Dilutions
Western Blot 0.1-1 µg/ml | ELISA 0.01-0.1 µg/ml | Immunoprecipitation 2-5µg/ml | IHC 2-10µg/ml | Flow cytometry 5-10µg/ml |
品牌介绍
Abbomax成立于2005年，是一家专业研发、生产、销售分子生物学试剂和提供生物科技CRO服务的高科技公司。产品主要包括抗体（一抗、二抗、磷酸化抗体）、蛋白多肽、脂质体、ELISA试剂盒、CellMax™ FFPE Cell Pellet Slide、TissueMax™ FFPE Cell Pellet Slide 等。这些产品受到了学术界的*好评。部分产品的详细列表：abbomax授权代理货号产品规格价格（美元）CellMax™ FFPE Cell Pellet Slide - A549T2102035$ 49.00CellMax™ FFPE Cell Pellet Slide - BT474T2101055$ 49.00CellMax™ FFPE Cell Pellet Slide - CaSkiT2103025$ 49.00CellMax™ FFPE Cell Pellet Slide - CHL-1T2106055$ 49.00
