abbomax/STAT4(pY693)/100ug/500-12064
市场价：
¥0.00
美元价：
0.00
产品分类：
流式抗体
公司分类：
Flow_cytometry
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
STAT4(pY693)
Signal transducer and activator of transcription 4
Download Product PDFProduct Preparation
A synthetic peptide surrounding to the epitope-KGYVP-- with phosphorylation sites atTyr693 of STAT4 protein from human, mouse, rat, chicken dog and bovine origins.
Background
STAT proteins (Signal transducer and activator of transcription) belong to a family of cytoplasmic transcription factors that can be phosphorylated by a lignad binding to its cell surface receptor. Activation of STAT4 induces dimerization, nuclear translocation and DNA binding. STAT4 protein expression is restricted to the thymus, spleen and testis. Both tyrosine and serine residues on STAT4 become phosphorylated in response to IL-12 or IFN-a although serine phosphorylation is not required for DNA binding. STAT4 is activated in T-cells in response to the cytokine interleukin-12 (IL-12), and in NK cells by IL-2.STAT4-deficient mice display impaired IL-12 development of Th1 cells and enhanced development of Th2 cells.
PURIFICATION The Rabbit IgG is purified by site-modified Epitope Affinity Purification. | SPECIFICITY This antibodyrecognizesSTAT4 (pY693) with aphosphorylated sites of Tyr693. It does not cross-react with non-phosphospecific peptide. |
FORMULATION This affinity purified antibody is supplied in sterile Tris-buffered saline (pH7.2) containing antibody stabilizer. | STORAGE The antibodies are stable for 12 months from date of receipt when stored at –20oC. The antibodies can be stored at 2oC-8oC for one month without detectable loss of activity.Avoid repeated freezing-thawing cycles. |
Gene ID
6775
Applications/Suggested Working Dilutions
Western Blot 0.1-1 µg/ml | ELISA 0.01-0.1 µg/ml | Immunoprecipitation 2-5µg/ml | IHC 2-10µg/ml | Flow cytometry Not tested |
品牌介绍
Abbomax成立于2005年，是一家专业研发、生产、销售分子生物学试剂和提供生物科技CRO服务的高科技公司。产品主要包括抗体（一抗、二抗、磷酸化抗体）、蛋白多肽、脂质体、ELISA试剂盒、CellMax™ FFPE Cell Pellet Slide、TissueMax™ FFPE Cell Pellet Slide 等。这些产品受到了学术界的*好评。部分产品的详细列表：abbomax授权代理货号产品规格价格（美元）CellMax™ FFPE Cell Pellet Slide - A549T2102035$ 49.00CellMax™ FFPE Cell Pellet Slide - BT474T2101055$ 49.00CellMax™ FFPE Cell Pellet Slide - CaSkiT2103025$ 49.00CellMax™ FFPE Cell Pellet Slide - CHL-1T2106055$ 49.00
