abbomax/Desmin (pT76/77)/100ug/602-280
市场价：
¥0.00
美元价：
0.00
产品分类：
单克隆抗体
公司分类：
monoclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Desmin (pT76/77)
Desmin, Intermediate filament protein; CSM1, CSM2;
Download Product PDFProduct Preparation
A synthetic peptide corresponding to the N-terminus with a dual phosphorylated threonine (Thr76/Thr77) of human Desmin.
Background
Desmin is a major intermediate filament protein found exclusively in striated (skeletal or cardiac) muscle tissue. It belongs to a large family of class IIIintermediate filament protein, the main intermediate filamentin mature skeletal, cardiac and smooth muscle cells. Mutations in the gene encoding desmin are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. PKC (Protein Kinase C) and cAMP-dependent protein kinase can induce disassembly of the desmin filaments by phosphorylatingmultiple sites at N-terminus of desmin which can affectthe desmin filament structure which play a role in the regulatory process in assembly and turnover.
PURIFICATION The Rabbit IgG is purified by site-modified Epitope Affinity Purification. | SPECIFICITY This antibody recognizes ~55 kDa of human Desmin protein at dual phosphorylated threonine (Thr76/Thr77).It does not recognize non-phosphorylated peptides confirmed by dot blot. The other species are not tested. |
FORMULATION This affinity purified antibody is supplied in sterile Tris-buffered saline (pH7.2) containing antibody stabilizer. | STORAGE The antibodies are stable for 12 months from date of receipt when stored at –20oC. The antibodies can be stored at 2oC-8oC for one month without detectable loss of activity.Avoid repeated freezing-thawing cycles. |
Gene ID
1674
Applications/Suggested Working Dilutions
Western Blot 0.1-1 µg/ml | ELISA 0.01-0.1 µg/ml | Immunoprecipitation 2-5µg/ml | IHC 2-10µg/ml | Flow cytometry 5-10µg/ml |
品牌介绍
Abbomax成立于2005年，是一家专业研发、生产、销售分子生物学试剂和提供生物科技CRO服务的高科技公司。产品主要包括抗体（一抗、二抗、磷酸化抗体）、蛋白多肽、脂质体、ELISA试剂盒、CellMax™ FFPE Cell Pellet Slide、TissueMax™ FFPE Cell Pellet Slide 等。这些产品受到了学术界的*好评。部分产品的详细列表：abbomax授权代理货号产品规格价格（美元）CellMax™ FFPE Cell Pellet Slide - A549T2102035$ 49.00CellMax™ FFPE Cell Pellet Slide - BT474T2101055$ 49.00CellMax™ FFPE Cell Pellet Slide - CaSkiT2103025$ 49.00CellMax™ FFPE Cell Pellet Slide - CHL-1T2106055$ 49.00
